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Dec 10, 2025 • Most practice-relevant findings

Nature Medicine - AI SectionPractice-Changing

Intrathecal onasemnogene abeparvovec in treatment-naive patients with spinal muscular atrophy: a phase 3, randomized controlled trial

A single spinal injection of onasemnogene abeparvovec significantly improved motor function in untreated spinal muscular atrophy patients, offering a promising new treatment option.

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